产品货号:
Z28876
中文名称:
TEM4/ARHGEF17抗体
英文名称:
Anti-TEM4/ARHGEF17 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-TEM4/ARHGEF17 Antibody |
指标别名 | TEM4,P164RHOGEF,p164-RhoGEF,KIAA0337,TEM4,Rho guanine nucleotide exchange factor 17,164kDa Rho-specific guanine-nucleotide exchange factor |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | ELISA,WB,IHC |
基因名称 | ARHGEF17 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | TEM4 antibody was raised against a 18 amino acid synthetic peptide near the center of human TEM4.The immunogen is located within amino acids 910 - 960 of TEM4. |
计算分子量 | 222kDa |
成分 | TEM4 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | TEM4 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Rho GTPases,which are activated by specific guanine-nucleotide exchange factors (GEFs),play pivotal roles in several cellular functions.TEM4,encoding a protein containing 1510 amino acids,contains a RhoGEF-specific Dbl homology (DH) domain but lacks their typical pleckstrin homology domain.TEM4 is a Rho-specific GEF with novel structural and regulatory properties and predominant expression in the heart.It couples tyrosine kinase signals with the activation of the rho/rac GTPases,thus leading to cell differentiation and/or proliferation.Elevated levels of TEM4,TEM5,TEM6,TEM7 and TEM7R were also raised in breast cancer tissues.TEM4 could also prove to be useful targets therapeutically. |
Uniprot ID | Q96PE2 |
基因名全称 | Rho guanine nucleotide exchange factor (GEF) 17 |
蛋白名全称 | Rho guanine nucleotide exchange factor (GEF) 17 |
推荐稀释比 | TEM4 antibody can be used for detection of TEM4 by Western blot at 0.5 ~ 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples and Immunohistochemistry in human samples.All other applications and species not yet tested. |
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